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What is the Suggested SAM-e Dosage?

To support mood and emotional well being, start with 400mg/day of SAM-e Complete. Clinical studies indicate that benefits are most likely evident after 7-14 days of supplementation. If benefits are not achieved within two weeks, you may require a higher level of supplementation. To determine the proper level of supplementation that works for you, gradually increase the number of tablets (maximum 1600 mg/day) until benefits are achieved.

We asked nutrition expert Carroll Reider, M.S., R.D., the question, “When, and how do I take SAM-e?” Watch the video below for the answer.

SAM-e should be taken on an empty stomach to help it absorb. Lower doses should be taken once a day, about half an hour before breakfast. Higher doses should be split, with the remainder taken one-half to one hour before lunch.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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If you have a question about SAM-e, please visit our FAQ. If you have further questions specific to your situation, please feel free to contact the Nature Made Consumer Affairs Department at 1-800-276-2878 (M-F 7AM-4PM Pacific Time) or consult with your physician.