Precautions
- As with all supplements, patients should be encouraged to inform their healthcare practitioners about their use of SAM-e.
- Patients with bipolar disorder or severe depressive disorder should take SAM-e only under a practitioner’s care, since there have been reports of mood swings in bipolar patients not taking mood stabilizers. People taking prescription antidepressant medications should consult a healthcare provider before taking SAM-e. People who are on or have recently taken MAO inhibitors should not take any product containing SAM-e except under supervision.
- As with any supplement, pregnant or nursing women should not take SAM-e without consulting a practitioner.
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