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Q: Can I take SAM-e once a day no matter what the dose? If not, what are your recommendations?

Thanks for your question. I have some general recommendations, but please remember that we are all different and respond differently to different supplements and dosages. My first recommendation is to pay attention to your body. If you are experiencing good results with your one dose, then don't change that. If you are experiencing difficulty, then decrease your dose or take it two times a day. Many people experience great results taking SAM-e once per day 30 minutes before breakfast. The maximum dose per day is 1600 mg.

SAM-e has research in 3 different area: Mood, Joint and Liver.

Mood: General recommendation is 200-400 mg per day, increasing by 200 mg per week until positive effect occurs.

Joint: General recommendation is 200 mg, three times per day. Before breakfast, lunch and dinner.

Liver: Research on liver support was at 1200 mg per day.

Again, pay attention to your individual body and please check in with your physician before starting SAM-e Complete, they have a better idea of your overall health, history and medications.

 Also, SAM-e should not be taken if you have been diagnosed with Bipolar Disorder unless recommended by your physician.

Thank you!

Shannon Wright, MS, RD

Nature Made Registered Dietitian