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Q: If you forget to take SAM-e, should you double up the following day?

Thank you for your interest in SAM-e.  I would not recommend that you take double your normal dose, but to just resume your normal dose of SAM-e.  To help you to remember to take your SAM-e, keep it in your bathroom so you can take it ifirst thing in the morning after brushing your teeth.   It is best to take SAM-e on an empty stomach about 30-45 minutes before you eat.  Many people find their best results taking it in the morning before breakfast.  also, if you forget, no worries!  You can always take it 1 hour after you eat.   If you are taking a larger dose of SAM-e it can be taken twice a day.  For example, take one dose of SAM-e early in the morning, and the other dose in the afternoon.